Eosinophils Do Not Drive Acute Muscle Pathology in the mdx Mouse Model of Duchenne Muscular Dystrophy [INNATE IMMUNITY AND INFLAMMATION]

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Key Points

  • Eosinophils are prominent in quadriceps lesions of dystrophin-deficient mdx mice.

  • Muscle damage was evaluated quantitatively in mdx, mdx.PHIL, and mdx.IL5tg mice.

  • In these models, eosinophil infiltration is not driving acute muscle pathology.

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