NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death [MUCOSAL IMMUNOLOGY]

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Key Points

  • The differentiation of naive T cells into Th1 cells induces the expression of Nlrp6.

  • The expression of Nlrp6 by Th1 cells depends on the microbiota.

  • Nlrp6 deficiency in T cells activates caspase-1 associated with cell death.

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