An Antigen Capture Assay for the Detection of Mycolactone, the Polyketide Toxin of Mycobacterium ulcerans [NOVEL IMMUNOLOGICAL METHODS]

Key Points

  • Sets of mAbs specific for the macrolide toxin mycolactone have been generated.

  • Two selected mAbs enabled development of a highly sensitive capture ELISA.

  • The assay has potential for conversion into a rapid diagnostic test for Buruli ulcer.

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