Identification and Characterization of Zebrafish Tlr4 Coreceptor Md-2 [INNATE IMMUNITY AND INFLAMMATION]

We found a gene for Md-2, a key protein that senses bacterial products, in zebrafish.

Zebrafish Md-2 has functional and physiological similarities to amniote MD-2.

LPS sensing in zebrafish may be more similar to humans than previously thought.