IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming [INNATE IMMUNITY AND INFLAMMATION]

Key Points

  • Human IgG subclasses elicit distinct cytokine profiles by myeloid immune cells.

  • Subclass-specific effects are mediated by distinct metabolic reprogramming by FcRs.

  • IgG subclasses provide pathogen- and cell type–specific immunity.

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