IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming [INNATE IMMUNITY AND INFLAMMATION]

Human IgG subclasses elicit distinct cytokine profiles by myeloid immune cells.

Subclass-specific effects are mediated by distinct metabolic reprogramming by FcRs.

IgG subclasses provide pathogen- and cell type–specific immunity.