Maternal- and Fetal-Encoded Perforin-2 Limits Placental Infection by a Bloodborne Pathogen [INFECTIOUS DISEASE AND HOST RESPONSE]

Key Points

  • Perforin-2 plays a protective role in infections of the placenta.

  • Both maternal- and fetal-encoded perforin-2 contribute to protection.

  • Perforin-2 is differentially expressed in placental macrophages during infection.

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