Prolonged SARS-CoV-2 viral shedding in patients with solid tumors and associated factors

SARS-CoV-2 is a highly contagious virus and can cause potentially fatal complications in cancer patients1-4. Until now, the most accurate and common methods to detect active viral infection are: (1) a positive RT-PCR, (2) a serological test (IgM+ and IgG-), (3) or a positive antigen test5. Previous studies have characterized time length of viral shedding in immunocompetent patients6; however, there are scarce reports on immunosuppressed cancer patients. Aydillo et al. studied shedding of viable SARS-CoV-2 in transplanted hematological patients or those receiving CAR-T cell therapy7.

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