Re: Inadequacy of PCR genotyping in advanced non-small cell lung cancer: EGFR L747_A755delinsSS Exon 19 deletion is not detected by the real-time PCR IdyllaTM EGFR mutation test but is detected by ctDNA NGS and responds to osimertinib

Whilst not disagreeing with much of the factual content in the recently published letter by O’Sullivan et al. [1], we feel that their article fails to consider relevance in a wider clinical context whilst making unjustifiable comments/recommendations on the basis of a single (n = 1) and also atypical case report.